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Patients’ most frequently asked questions regarding ClariFix® cryotherapy.

What is ClariFix® cryotherapy?


ClariFix® cryotherapy is a treatment that utilizes cold temperatures to stop the source of chronic rhinitis symptoms.

How does it work?


Chronic rhinitis symptoms are caused by out-of-balance nerves, which may be sending too many signals to your nose, telling it to drip, run and swell more than necessary. Using cryotherapy, the ClariFix® device delivers cold temperatures to these out-of-balance nerves in the back of the nose, interrupting the signals and reducing your symptoms.

How long until I will see an improvement?


Most patients begin to see improvement between 2 and 6 weeks post-treatment.

What kind of results can I expect?


In a clinical study, patients reported a significant decrease in runny nose and nasal congestion with 4 out of 5 patients reporting long-lasting symptom relief.

How long does the treatment take?


You can typically expect to spend about an hour in our office.

What does the treatment feel like?


You may experience slight pressure, a cooling sensation in the nose and/or around the molars, or some discomfort during and/or after the treatment.

What can I expect during the treatment?


Your doctor will start by numbing the nose with anesthetic. The ClariFix® device is then placed in the back of the nose, and the cold therapy is applied.

Is there downtime?


Most patients typically return to normal activity the same day. As with any nasal treatment, you may experience increased sensitivity, congestion, and some discomfort after the treatment.

What are the side effects?


The most common side effects associated with ClariFix® cryotherapy are temporary increased congestion and transient pain or discomfort.
Adverse events were those usually associated with post-cryosurgery in nasal passageways and included: pain/discomfort, headache, facial pain, bleeding, dry nose, ear blockage. By day 90, symptoms had either resolved or rated as mild.

Should I continue my current medications after treatment with ClariFix® cryotherapy?


Your doctor will discuss your current medications with you and determine a treatment plan specific to you.

Can I be treated with ClariFix® cryotherapy if I’ve had a previous sinus surgery?


Your doctor will discuss your medical history with you, including previous surgeries and determine a treatment plan specific to you.

Is the ClariFix® cryotherapy device FDA cleared?


Yes, the ClariFix Device is cleared by the FDA.

FDA Indication: The ClariFix Device intended to be used as a cryosurgical tool for the destruction of unwanted tissue during surgical procedures, including in adults with chronic rhinitis.

Midwest Ear, Nose & Throat
2315 West 57th Street  •  Sioux Falls, South Dakota 57108  •  605-336-3503  •  Toll-free 888-336-3503  •  Fax 605-336-6010